Question

Which of the given statements is incorrect about Family and Domain Analysis?

(a) Gene identification of predicted proteins in the genome is designed to discover the metabolic features of an organism

(b) In a particular organism or group of organisms, one particular domain can be expanded to perform a particular function

(c) Comparison of the domain content of an entire proteome with that of another proteome cannot help in revealing the biological roles of diverse domains in different organisms

(d) Different proteins are mosaics of domains that occur in different combinations in a given protein

This question was addressed to me at a job interview.

Origin of the question is Comparative Genomics topic in portion Collecting & Storing Sequences in Laboratory of Bioinformatics

Answer 1

Right choice is (b) In a particular organism or group of organisms, one particular domain can be expanded to perform a particular function

Easiest explanation: In a particular organism or group of organisms, various domains can be expanded to perform a particular function. More than 2000 fly and worm proteins are multidomain proteins, compared to about one-third this number in yeast.