Right option is (b) Genes with a related function are frequently found to be distorted on a chromosome
To elaborate: Genetic analysis has revealed that genes with a related function are frequently found to be clustered at one chromosomal location. As genome-by-genome comparisons of the chromosomes of related species are made and the rearrangements are discovered, a further challenge to computational and evolutionary biologists is to estimate the number and types of rearrangements that have occurred and also to determine when they occurred. For example, a comparison of the mouse and human chromosomes reveals many rearrangements.