Question

What competes with substrate for active site?

(a) Competitive inhibition

(b) Uncompetitive inhibition

(c) Non-competitive inhibition

(d) Pure Non-competitive inhibition

This question was posed to me during a job interview.

Question is taken from Determining Enzyme Kinetic Constants from Batch Data in chapter Homogenous Reactions of Bioprocess Engineering

Answer 1

The correct answer is (a) Competitive inhibition

The best I can explain: When a fake substrate binds to the active site of an enzyme, it can’t be processed in the same way and it won’t turn into a product. A fake substrate is called a competitive inhibitor. Competitive inhibitors bind the active site of an enzyme, preventing a real substrate from binding and a product from being formed.