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Km is directly proportional to the rate of enzyme binding?

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Km is directly proportional to the rate of enzyme binding?

(a) True

(b) False

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The question is from Determining Enzyme Kinetic Constants from Batch Data in portion Homogenous Reactions of Bioprocess Engineering

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The correct answer is (b) False

Easy explanation: Km reflects the enzyme’s dissociation constant. A high Km means weak binding (the enzyme likes to dissociate from its substrate), and a low Km means strong binding (it doesn’t like to dissociate from its substrate, meaning that it has a strong affinity for the substrate).

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