Right choice is (a) True
The best I can explain: The value of kLa is unique to both the size and configuration of a reactor vessel. Although some empirically derived expressions have been published for predicting kLa values in non-Newtonian fluids, there is no agreed upon set of equations that account for all of the variables that can affect the results. Accordingly, predicting kLa is not possible, and kLa studies need to be performed for bioreactors individually. The kLa value will depend upon the design and operating conditions of the fermenter and will be affected by the variables such as
– aeration rate,
– agitation rate and
– impeller design.