Question

What is the pH of early endosomes?

(a) 5.0

(b) 4.5

(c) 6.0

(d) 7.5

I had been asked this question at a job interview.

This question is from Gene Therapy Using Viral Vectors in section Utilizing Genetically Engineered Organisms & Medical Applications of Bioprocess Engineering of Bioprocess Engineering

Answer 1

Right answer is (c) 6.0

The best I can explain: The intravesicular pH drops along the endocytic pathway, from pH 6.0–6.5 in early endosomes.