Question

Proteoglycans are the survival factor of viruses.

(a) True

(b) False

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Answer 1

Correct answer is (b) False

The best explanation: The proteoglycans have very high molecular weight. If the virus is concentrated by ultrafiltration, the proteoglycan is also concentrated by nearly the same factor. While the high virus concentration would be expected to increase the number of infected cells, the presence of concentrated proteoglycan leads to increased inhibition of infection, so that the number of cells infected does not increase significantly and in some cases even decreases with the concentrated viral preparation.