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Which of the following enzyme is responsible for initiating DNA replication?

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Which of the following enzyme is responsible for initiating DNA replication?

(a) polymerase

(b) ligase

(c) primase

(d) gyrase

The question was asked during a job interview.

Origin of the question is DNA Replication in chapter DNA Replication and Repair, Cellular Reproduction of Cell Biology

1 Answer

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Best answer
Correct answer is (c) primase

The best explanation: The enzyme primase is a type of RNA polymerase that is responsible for initiating DNA replication. This enzyme constructs a short primer composed of RNA, that serve as primers for the synthesis of DNA by DNA polymerase.

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