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How many prokaryotic DNA polymerases have 5’->3’ proofreading activity?

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How many prokaryotic DNA polymerases have 5’->3’ proofreading activity?

(a) 1

(b) 2

(c) 3

(d) 4

I had been asked this question in a national level competition.

This interesting question is from DNA Replication Prokaryotes topic in chapter DNA Replication of Cytogenetics

1 Answer

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Best answer
The correct answer is (a) 1

Explanation: Only DNA polymerase I has 5’->3’ proofreading activity. Other polymerases like pol II and III have 3’ -> 5’ proofreading activity. There are mainly 3 prokaryotic DNA polymerases.

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