Question

Which histone(s) are acted upon by HAT?

(a) H1, H2

(b) H3

(c) H2A, H2B

(d) H3, H4

This question was posed to me during an interview for a job.

I want to ask this question from Transcription in Eukaryotes : Chromatin Remodelling in section Gene Expression : Transcription Prokaryotes of Cytogenetics

Answer 1

Right option is (d) H3, H4

To elaborate: These are the two histone residues that are having lysine side chains available for acetylation. On, HAT action they loosely bind to DNA allowing transcription.