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If you study T4 bacteriophage transcription with holoenzyme which genes will you expect to be transcribed?

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If you study T4 bacteriophage transcription with holoenzyme which genes will you expect to be transcribed?

(a) Immediate early

(b) Early

(c) Delayed

(d) Late

The question was posed to me during an interview for a job.

This question is from Transcription in Prokaryotes : Sigma Factor topic in section Gene Expression : Transcription Prokaryotes of Cytogenetics

1 Answer

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Correct choice is (a) Immediate early

The best explanation: Sigma factor in holoenzyme ensures transcription of immediate early gene first soon after viral infection. This is followed by delayed and late gene transcription. Core  Enzyme shows no such specificity.

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