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While in vitro transcription your RNA pol is stalled at a position due to mistreatment. Which factor could you act to help the RNA pol overcome the stalled stage?

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While in vitro transcription your RNA pol is stalled at a position due to mistreatment. Which factor could you act to help the RNA pol overcome the stalled stage?

(a) TFIID

(b) TFIIF

(c) TFIIS

(d) TFIIH

The question was posed to me in examination.

My question is from Transcription in Eukaryotes : Transcription Factors in division Gene Expression : Transcription Prokaryotes of Cytogenetics

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The correct choice is (c) TFIIS

Explanation: TFIIS is the transcription factor that helps to overcome the transcriptional stalling of RNA polymerases and also to help the polymerase to backtrack.

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