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What is the fate of phosphorylated Cdc 6?

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What is the fate of phosphorylated Cdc 6?

(a) It is transported outside nucleus

(b) It is ubiquitinylated

(c) It gets activated

(d) It forms a complex with Cdt

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I'd like to ask this question from DNA Replication Eukaryotes in division DNA Replication of Cytogenetics

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Correct choice is (b) It is ubiquitinylated

Explanation: Cdc 6 after triggering initiation dissociates from ORC and is phosphorylated to prevent re-initiation. It undergoes ubiquitination and destruction while MCM is phosphorylated and transported outside the nucleus. It ensures that Cdc 6 and MCM remain inactive and can’t re-initiate replication.

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