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What is the DNA composition of ARS?

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What is the DNA composition of ARS?

(a) A-T rich

(b) G-C rich

(c) Repeating A-T, G-C sequence

(d) No specific sequence speciality

The question was posed to me at a job interview.

Origin of the question is DNA Replication Eukaryotes in portion DNA Replication of Cytogenetics

1 Answer

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Best answer
The correct option is (a) A-T rich

Best explanation: A-T bases bound by 2 hydrogen bonds unlike G and C, which are bound by 3 hydrogen bonds. In such region DNA strand separation is easier as compared to G-C rich regions. Hence, ARS which requires DNA melting to initiate replication is A-T rich.

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