Question

In DSB repair in G1 phase, which of these factors would be seen which is absent in other phases?

(a) RAD 51

(b) MRN

(c) RAD 23

(d) Ku 70/80

This question was addressed to me by my school principal while I was bunking the class.

This intriguing question originated from Repair of DNA Damage: Recombinational and Bypass in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

Answer 1

In the context of Double-Strand Break (DSB) repair during the G1 phase of the cell cycle, RAD 23 is a factor that would be seen in this phase but absent in other phases. RAD 23 is involved in the repair process by interacting with the nucleotide excision repair machinery and can also play a role in the DNA damage response during G1.

Thus, the correct answer is (c) RAD 23.