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How many Holliday branch points are produced during DSB repair?

(a) 1

(b) 2

(c) 3

(d) None

I had been asked this question during an internship interview.

This interesting question is from Repair of DNA Damage: Recombinational and Bypass in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

1 Answer

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Best answer
Correct option is (b) 2

The best explanation: In case of DSB there are two branch points produced. One where the 3’ overhang invades the homologous strand and other when it hybridizes with the other 3’ end.

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