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Patau syndrome is a result of which of the following?

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Patau syndrome is a result of which of the following?

(a) Non-disjunction of sex chromosome in female

(b) Non- disjunction of sex chromosome in male

(c) Non-disjunction of chromosome 21

(d) Non-disjunction of chromosome 13

This question was posed to me in examination.

The question is from Chromosomal Abnormalities : Aneuploidy topic in chapter Chromosomal Basis of Inheritance of Cytogenetics

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Correct option is (d) Non-disjunction of chromosome 13

To explain I would say: Non-disjunction of chromosome 13 will result in a trisomy and monosomy if the gamete is fertilized. This results in Pataeu syndrome. It is an autosomal aneuploidy.

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