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P53 requires ________________for its activity.

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P53 requires ________________for its activity.

(a) Mdm

(b) MCM

(c) Securin

(d) Cdt

This question was addressed to me during an interview.

I would like to ask this question from Overview of Cell Reproduction in section Chromosomal Changes During Meiosis of Cytogenetics

1 Answer

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Best answer
Right choice is (a) Mdm

The best explanation: P53 prevents cell cycle progression during DNA damage. This is mediated with the help of Mdm which helps it to induce transcription of p21 that helps prevent a continuation of cell cycle.

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