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Deletion of a region led to over expression of a gene X. What do you conclude from this observation?

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Deletion of a region led to over expression of a gene X. What do you conclude from this observation?

(a) Part of gene X is mutated

(b) Promoter of gene X is deleted

(c) Regulator of gene X is deleted

(d) No effect on gene X or its regulators

I have been asked this question in an international level competition.

Question is from Chromosomal Abnormalities : Deletion topic in chapter Chromosomal Basis of Inheritance of Cytogenetics

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The correct choice is (c) Regulator of gene X is deleted

Explanation: In this case over expression of gene X is due to deletion of some negative regulator like operon, insulator, silencer etc.

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