Question

The rate at which drug reaches the systemic circulation is determined by the slowest of the various steps involved in the sequence. This is known as ____________

(a) Disintegration time

(b) Dissolution time

(c) Rate limiting step

(d) Gastric Emptying time

I got this question by my college director while I was bunking the class.

I would like to ask this question from Drug Absorption in division Absorption of Drugs of Drug Biotechnology

Answer 1

Correct choice is (c) Rate limiting step

For explanation I would say: The rate at which drug reaches the systemic circulation is determined by the slowest of the various steps involved in the sequence. Such a step is known as the rate-limiting. Disintegration time is the time required for the drug to be broken down into smaller particles or aggregates. Dissolution time is the time required for all the drug disintegrated particle to dissolve in the fluid. Gastric emptying time is the emptying time of the stomach.