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When the intracellular iron level is low, the turnover of transferrin mRNA is________

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When the intracellular iron level is low, the turnover of transferrin mRNA is________

(a) Increased

(b) Decreased

(c) Kept normal

(d) Doesn’t effect

The question was asked in homework.

This interesting question is from Control of Translation in portion Gene Expression : Translation of Cytogenetics

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The correct choice is (b) Decreased

To elaborate: By turnover of mRNA the effective concentration of a protein can be decreased as it reduces the chance of translation. When already the level of iron is low, more transferring s required, so mRNA is stabilized and its turnover is reduced.

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