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Mitogens can control translation efficiency by acting on _____________ factor which ___________

(a) eIF4 factors which increases translation

(b) eIF4A factors which decreases translation

(c) eIF4E factors which increases translation

(d) eIF4G factors which decreases translation

The question was asked in an online quiz.

My question is from Control of Translation topic in chapter Gene Expression : Translation of Cytogenetics

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The correct option is (c) eIF4E factors which increases translation

Explanation: Mitogens cause phosphorylation of eIF4E-BP which binds to eIF4E and prevents translation. Thus, phosphorylation of the inhibitor will in turn promote translation.

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