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What is the body’s defence against electrophiles?

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What is the body’s defence against electrophiles?

(a) Their inactivation by conjugation with glucagon

(b) Their inactivation by conjugation with glutamine

(c) Their inactivation by conjugation with glucuronic acid

(d) Their inactivation by conjugation with glutathione

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My doubt is from Bioactivation and Tissue Toxicity topic in section Biotransformation of Drugs of Drug Biotechnology

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Right choice is (d) Their inactivation by conjugation with glutathione

The explanation: The body’s defence against electrophile is their inactivation by conjugation with glutathione, the most abundant cellular nucleophile wit –SH group. Example of tissue toxicity due to electrophiles is hepatotoxicity of paracetamol metabolites.

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