Question

Which of the following decreasing order of blood flow rate through the muscular tissue is in the right order?

(a) Arm > thigh > buttocks

(b) Arm > buttocks > thigh

(c) Buttocks > thigh > arm

(d) Thigh > arm > buttocks

I got this question during an interview.

The question is from Drugs Absorption from Non Oral Extravascular Sites in section Absorption of Drugs of Drug Biotechnology

Answer 1

The correct option is (a) Arm > thigh > buttocks

To elaborate: The decreasing order of the blood flow to the muscular tissue is in the order Arm > thigh > buttocks. The blood flow rate is a rate-limiting step in the absorption of drugs from i.m. sites. Most rapid absorption is from deltoid muscles and slowest from the gluteal region.