Question

How renal clearance ratio is expressed?

(a) Renal clearance of creatinine / renal clearance of the drug

(b) 1/renal clearance of the drug

(c) Renal clearance of drug/ renal clearance of creatinine

(d) 1/renal clearance of creatinine

I got this question in examination.

My question comes from Drugs Excretion topic in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer 1

The correct option is (c) Renal clearance of drug/ renal clearance of creatinine

For explanation: It is the clearance ratio of a drug with that of the clearance value compound which gets cleared by glomerular filtration only. Thus, the renal clearance ratio is expressed by clearance of drug/clearance of creatinine.