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What is the equation for biliary clearance?

(a) No such equation is there

(b) Biliary excretion rate/ plasma drug concentration

(c) Plasma drug concentration / biliary excretion rate

(d) Plasma drug concentration / Bile flow * biliary drug concentration

I got this question during an interview.

My doubt is from Drugs Excretion in division Prodrugs & Excretion of Drugs of Drug Biotechnology

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Right choice is (b) Biliary excretion rate/ plasma drug concentration

For explanation: The ability of the liver to excrete drug into the bile is expressed as bile clearance. The equation for bile clearance is biliary excretion rate/ plasma drug concentration. Since biliary excretion can also be written as bile flow * biliary drug concentration. The other equation for bile clearance is bile flow * biliary drug concentration/ plasma drug concentration.

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