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Downregulation of caspase 3 can lead to ovarian cancer.

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+1 vote
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in Cytogenetics by (679k points)
Downregulation of caspase 3 can lead to ovarian cancer.

(a) True

(b) False

I had been asked this question in an interview for job.

Origin of the question is Apoptosis and Cancer in section Cancer Biology & Methods in Cytogenetics of Cytogenetics

1 Answer

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Best answer
Correct choice is (a) True

To explain I would say: It has been reported that caspase-3 mRNA levels are appreciably downregulated in breast, ovarian, and cervical tumours. Low levels of caspases or impairment in caspase function may lead to decreased apoptosis.

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