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Which bond should be between the active drug and inert carrier?

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Which bond should be between the active drug and inert carrier?

(a) Covalent bond

(b) Vander Waal’s force

(c) Di-sulphide bond

(d) Ionic bond

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The correct option is (a) Covalent bond

Best explanation: This type of prodrug where the active ingredient and inert drug is bonded by the covalent bond comes under carrier-linked prodrug. They are generally esters or amide. These drugs and modified their lipophilicity to a great extent because of being attached to a carrier. The active drug is released by hydrolytic cleavage. The hydrolytic cleavage can be chemical or enzymatic.

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