Question

Prodrugs with two active compounds are known as ___________

(a) Mixed type prodrugs

(b) Pro-prodrugs

(c) Bioprecursors

(d) Mutual prodrug

This question was posed to me during a job interview.

My query is from Prodrugs in portion Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer 1

The correct choice is (d) Mutual prodrug

The explanation is: Pro-drugs comprising of 2 pharmacologically active agents coupled together to form a single product. It is made such that on acts as a carrier or other. Bioprecursors/ metabolic precursors are obtained after chemical modification of the active drug. The prodrugs are further derivative to a form where only enzymatic conversion to the prodrug has to be done before the later can be cleaved to give the active product are pro-prodrugs.