Question

What is the driving force for glomerular filtration?

(a) Concentration gradient

(b) Hydrostatic pressure of plasma

(c) High amount of aqueous pores

(d) Hydrostatic pressure of blood flow

The question was posed to me in unit test.

This is a very interesting question from Drugs Excretion topic in section Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer 1

Right choice is (d) Hydrostatic pressure of blood flow

The explanation is: Glomerular filtration is the 1st filtration in the urinary excretion. The driving force for filtration is the hydrostatic pressure of the blood flowing in the capillaries. 1.2 l/min of blood flows through the renal artery. The filtration rate is 120-130 ml/min through the glomeruli.