Question

What will be the rate of filtration if the rate of secretion is 0.9 ml/ sec, rate of reabsorption is 0.2 ml/sec and the rate of excretion is 2ml/sec for a particular drug?

(a) 3ml/sec

(b) 0.3ml/sec

(c) 1ml/sec

(d) 1.3ml/sec

The question was asked during an internship interview.

This question is from Drugs Excretion topic in division Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer 1

Correct answer is (d) 1.3ml/sec

The explanation is: The rate of excretion through the kidneys is given by the Rate of filtration + rate of secretion – Rate of absorption. Thus, for the rate of filtration, the equation becomes Rate of excretion – the rate of secretion + rate of absorption.