Question

Which of the following is synthetic nitrogenous local anesthetic?

(a) Cocaine

(b) Benzocaine

(c) Benzyl alcohol

(d) Clove oil

This question was addressed to me in examination.

My question comes from Mechanism of Action of Local Anesthetic topic in section Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

Answer 1

Correct answer is (b) Benzocaine

Best explanation: Natural anesthetic is cocaine. Synthetic nitrogenous local anesthetics are derivatives of PABA e.g. procaine, benzocaine, a derivative of acetanilide e.g. lignocaine, a derivative of quinoline e.g. cinchocaine, bucricaine. Synthetic non-nitrogenous will be benzyl alcohol and propanediol. Clove oil, phenol, chlorpromazine can also be used as a local anesthetic.