Question

Which of the following factor do not affect the absorption of local anesthetics?

(a) Vasodilating ability of drug

(b) Volume and concentration

(c) Vascularity of the tissue

(d) Presence of vasodilator

The question was asked in class test.

The question is from Mechanism of Action of Local Anesthetic topic in section Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

Answer 1

Correct answer is (d) Presence of vasodilator

To explain I would say: Many factors influence the entry of local anesthetic into the circulation some of these are vasodilating ability of the drug, volume, and concentration of the drug, vascularity of the tissues, the route of administration of the drug, the presence of vasoconstrictor.