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Check points in the cell cycle are dependent on __________________

(a) Time dependent regulation

(b) Volume dependent regulation

(c) Positive feedback regulation

(d) Negative feedback regulation

The question was asked in final exam.

The above asked question is from Cell Cycle Stages in division Cancer Biology & Methods in Cytogenetics of Cytogenetics

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The correct answer is (d) Negative feedback regulation

The explanation is: If the dependence was on positive feedback then it would be hard to differentiate between different levels of partially and fully positive cases. But in case of negative feedback, even one negative signal can be easily detected and its removal will trigger the process.

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