Question

In plasma drug concentration versus time graph as shown in the picture, what should be the correct option for the marked place?

(a) Maximum safe concentration

(b) Minimum effective concentration

(c) Tmax

(d) Onset of action

I got this question during an interview.

This is a very interesting question from Pharmacokinetic topic in division Pharmacokinetic Drug Interactions & Basic Considerations of Drug Biotechnology

Answer 1

Correct option is (d) Onset of action

To explain: It is the time needed for the curve to reach the peak. At the peak absorption rate is equal to the elimination rate. Thus, Tmax is the maximum required for the rate of absorption to be equal to the elimination rate.