Question

In which of the model peripheral compartments are connected to a central compartment?

(a) Compartment model

(b) Caternary model

(c) Physiologic model

(d) Mammillary model

The question was asked during an internship interview.

This interesting question is from Pharmacokinetic Models topic in portion Pharmacokinetic Drug Interactions & Basic Considerations of Drug Biotechnology

Answer 1

Right choice is (d) Mammillary model

The best I can explain: Mammillary model is the most common compartment model used in pharmacokinetics. This method has one or more peripheral compartments connected to the central compartment. The central compartment comprises of plasma and highly perfused tissue such as lungs, livers, kidneys, etc.