Question

How can you understand that a patient has a Barrett’s Esophagus?

(a) When the esophagus starts getting thinner

(b) When the oesophagus is no more having the peristaltic movement

(c) When upper oesophagus gets lined by red coloured tissue

(d) When lower oesophagus gets lined by red coloured tissue

I have been asked this question in an interview.

The question is from Pharmacotherapy of Peptic Ulcer in section Histamine, Bradykinin and their Antagonists, Pharmacotherapy of Gastric Ulcer, Peptic Ulcer of Drug Biotechnology

Answer 1

Right answer is (d) When lower oesophagus gets lined by red coloured tissue

To explain: GERD or Gastro Oesophageal Reflux Disease has many severe complications such as severe chest pains, bleeding or a pre-malignant change in the lining of the esophagus called Barrett’s esophagus – can result in adenocarcinoma. Barret’s esophagus causes histological changes in the cells lining esophagus associated with adenocarcinoma of the esophagus.