Question

What is GERD?

(a) When the lower esophagus sphincter does not open

(b) When the lower esophagus sphincter is not at all present

(c) When the acid from the stomach flows back to the oesophagus

(d) When acid in the stomach is not produced in a sufficient amount

The question was posed to me in an online interview.

This question is from Pharmacotherapy of Peptic Ulcer in chapter Histamine, Bradykinin and their Antagonists, Pharmacotherapy of Gastric Ulcer, Peptic Ulcer of Drug Biotechnology

Answer 1

Correct option is (c) When the acid from the stomach flows back to the oesophagus

Explanation: GERD or Gastro-Oesophageal Reflux Disease is when acid and pepsin from the stomach flows backward up into the esophagus often called heartburn. Gastric juice contains both acid and pepsin. Acid is believed to be the most injurious component of the refluxed liquid. Pepsin and bile may also damage the epithelial lining of the esophagus but their role is less clear than that of acid.