Question

Which of the following correctly defines a peptic ulcer?

(a) When the esophagus starts getting thinner

(b) A benign lesion of gastric mucosa

(c) When upper oesophagus gets lined by red coloured tissue

(d) When lower oesophagus gets lined by red coloured tissue

I have been asked this question in homework.

Question is taken from Pharmacotherapy of Peptic Ulcer in chapter Histamine, Bradykinin and their Antagonists, Pharmacotherapy of Gastric Ulcer, Peptic Ulcer of Drug Biotechnology

Answer 1

Right choice is (b) A benign lesion of gastric mucosa

Explanation: A benign lesion of gastric or duodenal mucosa occurring at a site where the mucosal epithelium is exposed to acid and pepsin. It can be caused by excess acid production or an intrinsic defect in the mucosal defence barrier. High levels of acid production, weakness in the mucosal layer, abnormal non protective mucus production.