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What is the full form of SAD?

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What is the full form of SAD?

(a) Secure Assessing dose

(b) Single Ascending Dose

(c) Sodium Ascending Dose

(d) Single Amount Dose

I had been asked this question by my school principal while I was bunking the class.

My doubt is from Controlled Release Medication in division Controlled Release Medication of Drug Biotechnology

1 Answer

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The correct answer is (b) Single Ascending Dose

To explain: Single Ascending Dose studies are those in which small groups of subjects are given a single dose of the drug while they are observed and tested for a period of time and MAD is Multiple Ascending Dose studies are conducted to better understand the pharmacokinetics & pharmacodynamics of multiple doses of the drug.

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