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What is the full form of MAD?

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What is the full form of MAD?

(a) Multiple Ascending Dose

(b) Managing Abnormalities Dose

(c) Managing absorption dose

(d) Managing Assimilation Dose

The question was asked in examination.

The above asked question is from Controlled Release Medication in division Controlled Release Medication of Drug Biotechnology

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Right option is (a) Multiple Ascending Dose

Easiest explanation: Multiple Ascending Dose studies are conducted to better understand the pharmacokinetics & pharmacodynamics of multiple doses of the drug and SAD is Single Ascending Dose studies are those in which small groups of subjects are given a single dose of the drug while they are observed and tested for a period of time.

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