Question

Which of the following is a drug for diabetes mellitus?

(a) Thiazolidinedione

(b) Acetanilide

(c) Thiazide-thiazide like diuretics

(d) Amlodipine

The question was posed to me in a job interview.

This question is from Controlled Release Medication in chapter Controlled Release Medication of Drug Biotechnology

Answer 1

Correct answer is (a) Thiazolidinedione

To explain I would say: Thiazolidinedione sensitizes peripheral tissues to insulin, inhibits glucose production and improves sensitivity to insulin in muscle, and fat tissue. Used in obese diabetics. Example of such drugs is Rosiglitazone (Avandia), Pioglitazone (Actos).