Question

Which of the following sentences can define clearly an insulin analog?

(a) Fully synthetic molecules

(b) Modified to act slower or faster

(c) Similar to bovine insulin used in other animals

(d) Drugs which have a similar structure to the insulin

This question was addressed to me in an interview for job.

Question is taken from Controlled Release Medication in portion Controlled Release Medication of Drug Biotechnology

Answer 1

The correct option is (b) Modified to act slower or faster

To explain I would say: An insulin analog is a chemical compound that is made by deletion, substitution, the addition of amino acids or a chain to the parent insulin molecule. The parent chain of insulin has 51 amino acids. Too make it fast acting or slow acting or to increase its half-life researchers try to create different forms of insulin analogue.