Question

Which of the following insulin analogue was approved by the FDA and marketed by Novo Nordisk?

(a) Lispro

(b) Insulin Aspart

(c) Glulisine

(d) Glargine

I had been asked this question during an internship interview.

Question is taken from Controlled Release Medication in section Controlled Release Medication of Drug Biotechnology

Answer 1

Right option is (b) Insulin Aspart

Explanation: Insulin aspart was approved by the Food and Drug Administrations (FDA) in 2000 and is marketed by Novo Nordisk under the brand name NovoLog. The amino acid, B28 of the parent insulin peptide chain, which is normally proline, is substituted with an aspartic acid residue.