Question

What are the characteristics of intestinal release systems?

(a) Release the drug along the entire length of GIT

(b) Prolonged their residence in the GIT and release

(c) Usage of polymers that dissolves only in the alkaline pH of colon

(d) Use of enteric coating

The question was asked during an interview for a job.

Question is from Biopharmaceuticals topic in chapter Biopharmaceuticals of Drug Biotechnology

Answer 1

Right option is (d) Use of enteric coating

To explain: A drug to make it release only in the intestine are enteric coated. The reason of such drugs to prevent gastric irritation, prevent destabilisation in gastric pH. Selective release of the drugs to Peyer’s patch of intestine prevents them from getting destroyed by the intestinal enzymes.