Question

Which one of the following should not be a characteristic of the vehicles or polymers which are used for parenteral formulations?

(a) Sterile

(b) Consists of pyrogen

(c) Nonirritating

(d) Biodegradable

The question was posed to me in an international level competition.

My enquiry is from Biopharmaceuticals in chapter Biopharmaceuticals of Drug Biotechnology

Answer 1

Right option is (b) Consists of pyrogen

The explanation is: The vehicle, polymers, and other substances which are used in parenteral formulations must not contain any pyrogen, sterile, non-irritating, biocompatible and biodegradable into nontoxic compounds within the time preferably close to the duration of drug action.