Question

What is the meaning of thymus independent B-cell activation?

(a) Without the participation of T-cell

(b) Do not mature in the thymus

(c) Thymus would not take part in its activation

(d) Affinity maturation takes place in the thymus

This question was posed to me by my college professor while I was bunking the class.

Query is from B-Cell topic in chapter Immunology of Life Sciences

Answer 1

Right choice is (a) Without the participation of T-cell

For explanation I would say: In thymus independent B-cell pathway, antigen activates B-cell without the participation of TH cell. Response generated by thymus independent antigens only generate IgM and do not give rise to memory.