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The conversion of phthalamide to phthalimide is brought about by the loss of ______ molecule.

(a) one H2O

(b) two H2O

(c) one NH3

(d) two NH3

The question was asked at a job interview.

This intriguing question originated from Carboxylic Acids Chemical Reactions in division Aldehydes, Ketones and Carboxylic Acids of Chemistry – Class 12

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Best answer
Right option is (c) one NH3

The best explanation: Phthalic acid on reaction with NH3 forms ammonium phthalate, which on heating loses two H2O molecules, one from each COONH4 group, to form phthalamide. This on further strong heating loses one NH3 molecule to form phthalimide, which is an imide derivative of phthalic anhydride.

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