Question

The scale-up process is preferred to which condition?

(a) The migration of a process from the lab-scale to the pilot plant-scale

(b) The migration of a process from the bench-scale to the lab-scale

(c) The migration of a process from the small-scale to the lab-scale

(d) The migration of a process from the bench-scale to the small-scale

This question was posed to me in unit test.

Asked question is from Steps in Bioprocess Development : A Typical New Product from Recombinant DNA in chapter Bioprocess Development of Bioprocess Engineering

Answer 1

Correct choice is (a) The migration of a process from the lab-scale to the pilot plant-scale

Easy explanation: In scale-up process, product and process development tend to move forward in small steps, this reduces the risk with larger investments in the next step and production level improvement.