Question

The ability of importins and exportins to transport molecules in and out of the nucleoporins is regulated by ______________

(a) ATPases

(b) GTPases

(c) AMPases

(d) Both ATPases and GTPases

I have been asked this question in an internship interview.

Question is from Nucleus in chapter Nucleus & Aerobic Respiration of Cell Biology

Answer 1

Right choice is (b) GTPases

For explanation I would say: Impotins and exportins are responsible for the transport of molecules inside the nucleus and outside to the cytoplasm respectively. This transport is regulated by GTPases, enzymes that hydrolyze guanosine triphosphate (GTP) to release energy. The major GTPase used in nuclear transport is ‘Ran’, which can bind either GTP or GDP.